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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ddfb8b0b4cfb56bd9c400977664c3aa9d5807036d15b8e2520443756695cf61' 
  AND token = '4epy0o8GGTKTZ+4WDG3PO8Tm9ltrh2WkMpEJa9c0Agk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}