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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '527c11f86986674802d01524d1f22b8e05e7d2a9c20399707e8d7cf760a88527' 
  AND token = 'ULV3B9teuYAgqHtvkmeP01T3jIS3hEpkj2VkytLe2Qc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}