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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d687fa14e374a141111728dd2c41102c2c7995fa97c508f5d4c5b6a504e8646' 
  AND token = 'oJdn9QgA8w/gJD/XpccBiN7j3c0NoG6cok/NjY4DnQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}