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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01812aed97bbe5a2f8aba2f03f29c1c2c45a913d5b39ca0e29af0ba22538f1c5' 
  AND token = 'MhfRiI0n98C4aWD8ayhwezv0IiBn+pGRU+7qIvpec9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}