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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38fdb80a4c07fa31ca28d2b2e9ef8f5837226325744960445f6ac0f38184178c' 
  AND token = '8PO1l+5Y/eaDolvh4nD4Q5SeHD6NMZZq/FO4+aIEcm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}