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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e651456304bc59f27e1e715e9bfe57e992d5b4997b527e54471a9ca78f193ef' 
  AND token = 'EEyXYLUYehMArr/WAii1EhR43lr3N+wSBS4di7Eu7Lo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}