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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51abc3b14ec9bb2c19ff191fffb6ffdcedc4fbe020b567d018d4272c8de34465' 
  AND token = 'DrQw8xO5saBjn9rP85/PPWKqHTyRL9brCPPfKgscS90=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}