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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21adf26a724cd7a1b2c28c2c89ec108b1222717004ee0b0447c658715e083fae' 
  AND token = '8yGc0MsMki+c+5KN9jF614YiUbzEw3tulW18NfW0fPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}