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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5ac5be7a75c0255abd1944e973ce39114ff17296a11f1d7d4a67b1590aa3b97' 
  AND token = 'gDnvCVvDcYFx4D4G1VdaG5fDIIhln5xL03HbhSJm7Dg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}