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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4967d6bb968d58ae9ed01402d9486b82b5b6839fb566d65328940b93182b1052' 
  AND token = 'JGODnfJ+zcrLQZ286HJEirkokEUVLT6mN8cxwAOUBaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}