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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e10552a810aad5dcc3b385a58340e19a663c4e76aef4e864627eb3d34813b57a' 
  AND token = 'VWiLyfeR1R3ho5nxpRXKCQumG0eXWZ7VdZP6Gd+s+xY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}