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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c145bcb0c04078d4659486fdcb46cd74b06c1b1296de09c1fc42e2f71d4a2c0' 
  AND token = '3iikOwb3+7e3JGgyUpWYoDjcrcep8jj4h2sDz5zA0u8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}