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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a395e74b19866fd0addbb33297e04b71381edc648333e37f24efbc7dfaa4ae43' 
  AND token = 'Jqpm4t/o7jHdsR9kIl4toJxSzNXArDVJIGvNX9NjO6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}