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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cefe7c0fb69cb19fe7a401f196f76c38768eff93689ca739436d2b952d3da4b1' 
  AND token = 'aC0+rFxzILN/BhW0WvkR920WcLMYqLlv3CPw6iBMTpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}