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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78cda86b79aaaadb2e17dbbe5126da49803f2fbe15fa543b488e4ec9d9048922' 
  AND token = 'HwSZh08L6f1zg2ivkbiic28rV1qZdxaOpI0BrYFi7bw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}