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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5281386539b4adc327bd68cdbc637a26b43442fadce0c7d900e08cd51634cfc1' 
  AND token = 'GbVwhimp9f+Ij950w6YTF9bsFsCrom2GAX4T5JIh+Pg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}