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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5c303499a3f80a8bfc3e8c939e188c51d97ddf4da5b550fa028f60b2fef0e7c' 
  AND token = 'ighe2gHw2A9CzZzmHPeWAAKB25WLVrauC+MfM09CQmk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}