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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '627b919a3282d49d0fab16f3b5d2e3f67c08665e301d065d9e725598083666a8' 
  AND token = 'MXwtrMcFC5mMzGm/UbrEWisZtmD7fngomcnbu6u87qw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}