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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10e6f65e18b52448be04f2a95f19b6c2b411340961da82d0acb3f9c603c1878d' 
  AND token = '17ArxC5uMTdeJE/HRwKWmSkDeObTZB2mBhWoH6tk/gY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}