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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8824c6b9e112fcd31bf938a090102af468cf71091eacf4b35c340c766b1fa10d' 
  AND token = 'DhyJf38NpqmemSn3/UyCri/iMnBWPb9cYKTsFyw3DtY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}