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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7133daae412233072d5afbeba822ed8a654670af7a55393c71226cecf25b1e98' 
  AND token = 'qIvwKD6FfDG+Qg+IGZEtKBxTDcsx6KQnmyta1KfTxbo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}