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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6f3b9622f519f52cb657401d45afd38393f21c4e30237b129012a48f558f5bb' 
  AND token = 'mWdwz+9Pr7jNgDfRCjcXYbVyOb3dqOaczbQJCCu801w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}