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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a41a065ae2917def825a112bb52675a51f26bcb9ab89bf242d800e80afc2677' 
  AND token = 'r7Cgz9d9TTulJBpS/H8zv+eAntaaFdi87oXwsdIHH/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}