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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70374bd5b3b3bcf77d8b23d55ab35a6f679b370881e740d56b68ea96ce59a865' 
  AND token = 'iGkKUS4Cvt0EKQrc8DD2DsMMuzsIoQ5xCXBex4a6kzo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}