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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '480fbe46a7a5c9238fadc38cc82007d06dfb6904196dd8974db55701f47942f1' 
  AND token = 'CUrM9u93Ib4S7MQODtD7H8qHQfVPeAa5XbDrZ2OMr1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}