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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '645214f98cc2a3162e3a1ac11af68e0ffff308f764fb0449729290e1ad030c03' 
  AND token = 'Ry+4c2N02gs0BQJQ0pUkVmFlDIfUQMm/PSY6Z8gCiiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}