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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee4f8a88f3896a54502ff856cc71310cd391d509e7fde8a69694300d816f8ede' 
  AND token = 'GqLEixZAqWCIVtbS+yHudks+Ws3ziPuqjFVFyHDViLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}