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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b16bda491ccb188020484a115932795068f6e5713df6ca7252f744aa1fba8f1' 
  AND token = 'MI/mcP0DdAFc6tl9Y8MONgql0lu4kVVnqX3aMgfvtMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}