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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40d80975a4658f2b7661ab79bd2aa3bb8003a75a5cdfe83fe5ec56e6b5aff51a' 
  AND token = '22miHvvnr2njIa7T6VKaaOG620lEAbgfHfsrMi2KN0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}