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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd372740c4d6d56a85a7f22369b0b71a33f80390e5a9f42b77c238270a0bee33' 
  AND token = 'r7ufLQ1RQ7Unlg2R/I2nlfoMgIL3VFvmiYbKf9691f4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}