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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a559f0176b0d8db0ffe5ba789d31d0a9e8f1f788e19d6dd5a45adf63d2fca93' 
  AND token = 'DqhTuzium5f1L5+HBBH4i/j/cVh2XAK4fx3nhSzlL2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}