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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c58d0b33b5f96ab21a5c4c8549536a6956e777b7b5d6f3214c05670fcea3146e' 
  AND token = 'IQcsgi1W922WM+44CPNFTxEthArb3b8syOehsgDDLLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}