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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '301d53001d69860e447870d661eeda7dbe991254335929ca14c1a1f1b468ed14' 
  AND token = 'gUUrDbZIoOAiG499oOYjBa7SiKKoLuG2sj9g+chVqjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}