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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9449c1923ba25824ed7f4a90c8ad2e6bdc68f541a12609c2b919051097a87e41' 
  AND token = '3Z2WQZe+Gm+qwIb1nnDnHcny1GR/U9EdwfYkjuxwuoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}