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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '949bcfe5e81c96c289e479829c0109335f9ed0c20b1ae65e2fb8893dd7006ce0' 
  AND token = 'nhBmivuwxcjgv1QwKmIWVbnj27r7EAzKZ3Z+BEncAzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}