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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed699f6f0cea77a646329a5d9e5c46705da82a9453ecb8b8e50c21ec4d027aba' 
  AND token = 'MN7RLO6bsI/VxrUVZmAhYDFYF0wr1qSdl6nBo2NM6X8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}