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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '291650aafcd0ef7e47c71a25d79f92922dbfcdcca4e91223457a7adfb0f5a70b' 
  AND token = '7PEUlvBjFM6n+oWTJIwT+m1VfPRGGZDbpCG8uTYWOEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}