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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8053043711b3fb0135639459fd42860f06c395db4a63d8ecd4d51c2423ed78de' 
  AND token = '+b4xmH23xuazLz6mgx2jyqu7fdf2VY9j6FTc8pG2gvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}