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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2415925c19164d8f8a27f80c0f62378d1239c5d4950676d8ec7a0f2850c397f7' 
  AND token = 'WX9Rl+ZGq42sAFVbxNv9gR1qfkUDM2xa4CeCaKtSIxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}