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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e6b542f0ba59dde69bd63bbc27ee772bffaa03892cfa8be5e4bccfdf9be240a' 
  AND token = 'gbMDTY2hfmWGN0eiyXyHXlSai+BrTNih7F49P5oghUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}