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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9146e26654abeaf8de6fa5e5220fb0322bc9955bc9939b701ff095cfa4f37463' 
  AND token = 'B6XgAaRVTe5TxS3pBLrdSVzSTiO/1evAOdOdFT6vyzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}