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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c61c8af064dc738cbdc6b928621ecfe82e3bcf7456025c60a5ce07087f220b7' 
  AND token = 'hyoizIWyCvGRccPWZGZySpz5ZzBHIXDZtX32yWpncOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}