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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bf71a8bc22e9abaf3055da153b7cd188c456b3dd47557289b2d607dd78d7fd2' 
  AND token = 'Gtz8xI68mE2QAcvvU/iwZ0aZbB7caMRSQpKuFhmmzjE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}