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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '992361506025de9e2c8a7cecc110925bf9be7acce549a98d9bb2a43226a1f68d' 
  AND token = 'DHlZIJ/8cl0YtfaGDw26Q8AIdTMBRGOkWhobqu+GFnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}