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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35c690d20174049a1978c85c1134d0a083c4721c4942268ce13b82424b0d9a31' 
  AND token = 'nxCGNTFAUIwmuTwGKxEC648rr7pbnfnez2dTNlwK8ds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}