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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81d1ba376da7a58dcdf5d16e4b4340984c19b1c75f54cdebcc58af26727105d6' 
  AND token = 'xWpCfqapSIC1cTreKrBZkjHcDX0kTVejDSn2jOiR7TQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}