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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c33a6a8707db3bcff3af0b589a0beb872216fd01c6efc2a05e3f2ec50c0cd8db' 
  AND token = 'z32nlHc7qwOgRHuCQjpzTmLZF9P6IQopWv6l4AJJOPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}