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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73644bf392904dc89392b9270f4a141d134b67ed3cda5ca9048bc50adf0404d1' 
  AND token = 'L40OIFwRsxn9qgQJBe1fO+RZPu5h6aVMLCxgq5yM49Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}