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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17279c6f45580b81c5ce65b23bb311e4292ef41adb778e386fdcb8825096928d' 
  AND token = 'ZHqONAZnmS2KZthC8Ze7/5et91QZdf7Dj2WkJ9Lq6ws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}