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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da8a16f7182124bda95388cc4f282a5efe33588b6e7f86e7f25e5a06f1dd2330' 
  AND token = 'mLW9RsVQ+XWSYXWUkSPp1hbyHMNVx2YguhAqmLUFbDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}